How drinking grape juice can be dangerous when you take certain drugs?

• In the intestine there is cytochrome P450, which is part of the detoxification system that detoxifies foreign materials (the drugs) going into the body
• Thus, in normal condition, some of the drugs are metabolized (which means becoming less) in the intestine before it goes into the circulation

• Grape juice inhibits cytochrome P450
• The intestine could not metabolized the drugs as it normally does
• There will be high quantity of the drugs going into the circulation
• This means overdose of drugs
• This means danger